International Journal of Biology Research


ISSN: 2455-6548

Vol. 2, Issue 1 (2017)

The effects of Mentha crispa on the spermatogenesis of wild rats (Rattus norvegicus) from Sudan

Author(s): Eitimad H Abdel-Rahman
Abstract: The health benefits and inadequacies of the Mentha species have already been demonstrated, but spearmint quality and composition vary in different species, places and still has to be studied. In Sudan, peppermint (Mentha crispa) is widely consumed for different purposes, but has not been used as a male infertility contraceptive agent. The objective of this study was to examine the effects of this plant on the body and vital organ weights of wild rats (Rattus norvegicus; n= 30), as well as sperm parameters and spermatogenesis, based on the administration of an aqueous extract of M. crispa for 60 days. The results of the present study showed that the average body weight decreased significantly in the experimental groups, for animals that received 50 and 100 mg/kg/rat of M. crispa extract, as compared with the control group that received only distilled water. There was no significant difference (p˃0.05) in the kidney, spleen, heart and liver weight of rats, as well as in the reproductive organs (testis, epididymis, prostate and seminal vesicle) in the experimental groups. However, there was a significant difference (p˃ 0.05) in sperm count, sperm viability and sperm motility (%) in the experimental groups. These findings suggest that the aqueous extract of M. crispa has inhibitory effects on male spermatogenesis (sperm phenotype and quality) which could be useful in the development of male infertility contraceptive agents and free rodenticides, in the sustainable management of rodents.
Pages: 16-19  |  1368 Views  629 Downloads
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