International Journal of Biology Research

ISSN: 2455-6548

Vol. 3, Issue 1 (2018)

Synthesis, characterization of biologically active Schiff base 14-membered M (III) macrocyclic complexes derive from 1 H-indol and diethyl oxalate and thiocarbonohydrazide

Author(s): Gajendra Kumar, Vidhi Singh, Preeti Sharma
Abstract: Biologically active Cr(III), Mn(III) and Fe(III) macrocyclic complexes [{M(C38H28N12S2)X}X2] of Schiff base ligand (C38H28N12S2)obtained through the condensation of thiocarbonodihydrazide, 1 H-indol and diethyl oxalate with the molar ratio 2:2:4. The structure configurations of the newly synthesized compounds have been determined by various spectroscopic: Electronic, IR, 1H NMR, 13C NMR, GCMS techniques and characterized with the help of magnetic measurements, elemental analysis, and condensation measurements. The electronic spectra of the complexes indicate a five coordinate square pyramidal geometry of the center metal ion. These compounds were tested for their antimicrobial inhibition potential against the bacteria: Staphylococcus aureus, Bacillus subtilis, Escherichiacoli, Salmonella typhi, Pseudomonasaeruginosa.and fungi Rizoctonia sp., Aspergillus sp., Penicillium sp.
Pages: 188-194  |  847 Views  403 Downloads
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