International Journal of Biology Research

Authors
Aashaq Hussain Allaie, Ravi Prakash Mishra, Aijaz Ahmad Ganaie, Shoket Ali, Ranu Singh

Abstract
Background: To investigate the antibacterial activity of crude hexane extract of Juglans regia against five clinical isolates of urinary tract infection. Urinary tract infections (UTI) caused by bacterial pathogens have become a serious global health concern. Clinical isolated bacterial agents responsible for UTI are Escherichia coli, Klebsiella pneumonia, Staphylococcus saprophyticus, Proteus mirabilis and Pseudomonas aeruginosa. Recently, medicinal plants have discovered extraordinary fame in therapeutic treatment for various types of diseases including urinary tract infection. Medicinal plants may be considered as new sources for producing antibacterial. Anti-bacterial study was carried out by disc diffusion method against the pathogens viz., Escherichia coli, Klebsiella pneumonia, Staphylococcus saprophyticus, Proteus mirabilis and Pseudomonas aeruginosa. maximum degree of antibacterial activity was seen against E. coli (22 mm) followed by Proteus mirabilis (17 mm) and Klebsiella pneumonia (16 mm) moderate activity shown by Pseudomonas aeruginosa (12 mm) and least activity shown by Staphylococcus saprophyticus (07 mm). In this way, the utilization of J. regia for treatment of urinary tract infection might be fulfilled. Additionally work will emphasize the isolation and characterization of dynamic standards in charge of bio-efficacy.