International Journal of Biology Research

International Journal of Biology Research


International Journal of Biology Research
International Journal of Biology Research
Vol. 1, Issue 2 (2016)

Histopathological responses of kidney in the common carp Cyprinus carpio exposed to sublethal concentrations of phorate


Lakshmaiah G

Cyprinus carpio (C. carpio) fish were exposed to chronic sublethal toxicity (one-tenth of the LC50/96 hours - 0.071 ppm/l) of phorate (CSTP) for 1, 7, 15 and 30 days and the effect of CSTP on kidney histopathology of the fish was investigated. On exposure for a period of 1 day to CSTP, glomerular Shrinkage and expansion of space inside the Bowman’s capsule was observed in the kidney of the fish. On exposure of the fish for a period of 7 days, destruction in the tubules, vacuolation in cytoplasm and loss of architecture were observed. Further on exposure of the fish C. carpio for a period of 15 days to CSTP, degeneration of glomerulus, increase in periglomerular space and degeneration in Bowman’s capsules were observed. After the exposure period of 30 days, indistinct capillary structure, shrunken glomerulus, tubular destruction, vacuolation in the cytoplasm, a clear increase in periglomerular space, loss of cell architecture and degeneration of cell nuclei were observed in the kidney of the exposed fish. The findings of the present study demonstrate that the frequency of pathological changes in the kidney of the fish C. carpio, increase with the increasing exposure time to CSTP.
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How to cite this article:
Lakshmaiah G. Histopathological responses of kidney in the common carp Cyprinus carpio exposed to sublethal concentrations of phorate. International Journal of Biology Research, Volume 1, Issue 2, 2016, Pages 55-59
International Journal of Biology Research