Euphorbia hirta belongs to the family Euphorbiaceae. It is a small annual herb and grows upto height of 40 cm. It is used in the treatment of many diseases such as bronchitis, skin diseases, cough, hay asthma, bowel disease, worm infestation, kidney stones, bronchial disease, as sedative, anxiolytic, analgesic, antipyretic etc. The phytochemical screening of petroleum ether and methanolic extracts shown the presence of components i.e., alkaloids, flavonoids, terpenoids, glycoside, saponin, tannins, carbohydrate and amino acid were present in the methanolic extract. It suggests that plant can be used in treatment of many diseases.