The monitoring of various enzyme activities during microbial inoculated composting and vermicomposting process provides helpful information on the dynamics of significant microbial activity is beneficial for understanding the conversion taking place. In this experiment, four different fungal species and two types earthworms were inoculated in different treatments of coir waste (CW) mixed with sugarcane bagasse (SBG) to study their effect on enzymatic activities, of the final product. The results suggested that uninoculated treatments did not show any significant effect on the activities of enzymes than inoculated treatments and vermicomposting. Inoculation of fungi significantly (p<0.05) increased the amylase, cellulase, protease, invertase and xylanase activities. The Inoculation of consortium, Aspergillus niger, Trichoderma viride and earthworms in initial CW with SBG registered the highest enzyme activity in the final product. The highest value of enzyme activity was recorded in MCT3, MCT4, MCT6, VCT7 and VCT8 treatments.