International Journal of Biology Research

Authors
Anil Kumar M, Vijaya K, Abhinava Vinay Kumar M

Abstract
Hemoglobinopathies includes sickcle cell anemia and thalassemia. Thalassemia is a disorder affecting the structure, function and production of Hb. Mutation in globin genes is the main cause for thalassemia1. In the present research work, 275 children, aged 3 -15 years were evaluated in Warangal Urban district and Mahabubabad district during the period February 2017 to November 2017. The blood samples of 275children were collected for the assessment of thalassemia. Few parameters like age, gender, social status and family history of their parents have been recorded. In the present research study we identified 29 children as thalassemia patients. Out of these 29 thalassemia patients we found 17 children born of consanguineous marriage of their parents. The results represented that one of the main impact factor of thalassemia disorder is consanguineous marriages between their parents. The aim of the present study was to evaluate the prevalence of thalassemia and to assess the effect of consanguineous marriages on the occurrence of thalassemia in Warangal Urban and Mahabubabad districts of Telangana state.