This paper deals with mineral analysis of Betel vine leaves infected with a fungus Cercospora piperis Sawada and Kutsuki. The leaf samples of healthy and infected material were air dried and digested by tri acid, according to the method of Toth et al., (1948). The acid digested samples were used for estimation of different minerals by Atomic Absorption Spectrophotometer (AAS) Perkin Elmer A Analyst model 300, while phosphorus element was estimated by the method of Sekine et al., (1966). The elements such as calcium, iron, manganese, zinc, cobalt, magnesium and copper contents were greatly enhanced in young and mature infected leaves of betel vine as compared to healthy. While the non-metal phosphorus found to be decreased in both young and mature infected leaves.