International Journal of Biology Research

International Journal of Biology Research


International Journal of Biology Research
International Journal of Biology Research
Vol. 3, Issue 4 (2018)

in vitro anti-oxidant activity and acute toxicity, of ethanol extract of root tubers of Asparagus gonoclados


Allagadda Rajasekhar, Kotha Peddanna, Chippada Appa Rao

The primary concern of this study was to assess the phytoconstituents of ethanol extract of Asparagus gonoclados root tubers and to evaluate the In vitro antioxidant activity and any possible toxicity of Asparagus gonoclados. Phytochemical analysis of Ethanol extract revealed the presence of phytosterols, flavonoids, phenols, tannins, steroids, triterpenes, and proteins. In vitro antioxidant activity of the ethanol extract of Asparagus gonoclados was analyzed by DPPH, NO and H2O2 methods, and the ethanol extract at the concentration of 100 µg/ml exhibited the highest activity. Acute oral toxicity tests were also performed in 4 groups of rats with ethanol extract administered orally at the doses of 2000, 3000, and 4000 mg/kg. bwt. No momentous changes were observed after 30 min and up to 24 h, which imply the nontoxic nature of the A.gonoclados root tubers. From the above outcome of the results, it is concluded that the ethanol extract of root tubers of Asparagus gonoclados possess impressive antioxidant and nontoxic properties.
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How to cite this article:
Allagadda Rajasekhar, Kotha Peddanna, Chippada Appa Rao. in vitro anti-oxidant activity and acute toxicity, of ethanol extract of root tubers of Asparagus gonoclados. International Journal of Biology Research, Volume 3, Issue 4, 2018, Pages 52-56
International Journal of Biology Research