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VOL. 10, ISSUE 1 (2025)
Advances in CRISPR/Cas-Based genome editing for crop improvement: A review
Authors
S B Verma
Abstract
The global population is on a relentless trajectory toward 10 billion
by mid-century, a demographic shift that places unprecedented pressure on
agricultural systems to increase food production sustainably and equitably.
Traditional crop breeding, a cornerstone of agricultural development for
millennia, is increasingly challenged by the rapid pace of climate change, the
emergence of new plant diseases, and the need for enhanced nutritional content
to address hidden hunger. The advent of CRISPR/Cas (Clustered Regularly
Interspaced Short Palindromic Repeats-CRISPR-associated) technology has
provided a powerful and precise solution to these challenges, revolutionizing
the field of plant breeding. This review focuses on the latest research from
the past five years (2020-2024), a period marked by a transition from
foundational CRISPR/Cas9-mediated gene knockouts to more sophisticated and
diverse genome editing strategies. We detail the technological innovations that
have made CRISPR more efficient and accurate, such as the refinement of base
and prime editing. We also present a comprehensive table of recent successful
applications across a variety of crop species, from staple grains to
horticultural products. This paper critically evaluates the ongoing challenges,
including technical limitations in delivery and specificity, as well as the
complex regulatory and societal hurdles that must be navigated for these
innovations to reach farmers and consumers globally.
Pages:57-60
How to cite this article:
S B Verma "Advances in CRISPR/Cas-Based genome editing for crop improvement: A review". International Journal of Biology Research, Vol 10, Issue 1, 2025, Pages 57-60
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